SLC6A11 Antibodies

AND SLC6A11 ELISA kits, SLC6A11 Proteins

Many biological assays use antibodies to detect SLC6A11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC6A11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC6A11 antibodies...

We validate the specificity of these antibodies to SLC6A11 by testing them on tissues known to express SLC6A11 positively and negatively. Browse below to find the SLC6A11 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC6A11 Infographic by Boster Bio

All SLC6A11 Products

Product

Figures

Specificity

Applications

Price

Anti-GABA T-3 SLC6A11 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A07460
100ul

SLC6A11 (NM_014229) Human Over-expression Lysate

Human

$960
Cat # LS006538
100 µg

SLC6A11 Overview

Facts about Sodium- and chloride-dependent GABA transporter 3.

SLC6A11 3D structure. Source: alphafold

Sodium- and chloride-dependent GABA transporter 3 (SLC6A11)

Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. .

Gene Information

Human
Gene Name:	SLC6A11
Uniprot:	P48066
Entrez:	6538

Family

Belongs to:

sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family

Alternative Names

GABA Transporter 3; GABT3; GAT-3; GAT3sodium- and chloride-dependent GABA transporter 3; GAT4; solute carrier family 6 (neurotransmitter transporter, GABA), member 11; Solute carrier family 6 member 11

Molecular Weight

Mass (kDA):
70.606 kDA

Genomic Context


Human

Location:	3p25.3
Sequence:	3; NC_000003.12 (10816200..10940714)

Tissue Specificity

Widespread distribution in the brain.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Epilepsy
Nervousness
Schizophrenia
Globus Hystericus
Pain
Neuralgia
Cholangiocarcinoma
Sclerosis
Disease Of Adrenal Medulla
Meningeal Disorder
Dyskinetic Syndrome
Dyskinesia, Drug-induced

Lymphoma
Dysequilibrium Syndrome
Epilepsy, Temporal Lobe
Involuntary Movements
Fibromyalgia
Anxiety Disorders
Ischemia

Pathways

Localization
Transport
Cellular Localization
Transmembrane Transport
Brain Development
Immune Response
Synaptic Transmission
Neurotransmitter Transport
Lateral Inhibition
Methylation

Neuroprotection
Reverse Transcription
Sensitization
Membrane Depolarization
Amino Acid Transport

PTMs

Biotinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC6A11

References

PMID: 7874447 by Borden L.A., et al. Cloning of the human homologue of the GABA transporter GAT-3 and identification of a novel inhibitor with selectivity for this site.