SNRPB Antibodies

AND SNRPB ELISA kits, SNRPB Proteins

Many biological assays use antibodies to detect SNRPB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SNRPB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SNRPB antibodies...

We validate the specificity of these antibodies to SNRPB by testing them on tissues known to express SNRPB positively and negatively. Browse below to find the SNRPB antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SNRPB Infographic by Boster Bio

All SNRPB Products

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Specificity

Applications

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Anti-SNRPB Antibody

Western blot analysis of extracts of various cell lines, using SNRPB antibody at 1:3000 dilution

Human, Mouse

IHC, WB

$405
Cat # A05674
100ul

SNRPB (NM_198216) Human Over-expression Lysate

SNRPB Human Over-expression Lysates NM_003091

Human

$628
Cat # LS006628
20 µg, 100 µg

Anti-SNRPB Antibody

Human

ELISA, IHC, WB

$370
Cat # A05674-1
100 μl/vial

SNRPB Overview

Facts about Small nuclear ribonucleoprotein-associated proteins B and B'.

SNRPB 3D structure. Source: alphafold

Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB)

Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Part of both the pre- catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).

Is also a component of the minor U12 spliceosome (PubMed:15146077). As part of the U7 snRNP it's involved in histone pre-mRNA 3'-end processing (PubMed:12975319).

Gene Information

Human
Gene Name:	SNRPB
Uniprot:	P14678
Entrez:	6628

Family

Belongs to:

snRNP SmB/SmN family

Alternative Names

CODB polypeptide of Sm protein; Sm protein B/B'; small nuclear ribonucleoprotein polypeptides B and B'; small nuclear ribonucleoprotein polypeptides B and B1; small nuclear ribonucleoprotein-associated proteins B and B'; SmB/B'; Sm-B/B'sm-B/Sm-B'; SmB/SmB'; snRNP-Bsmall nuclear ribonucleoprotein polypeptide B; SNRPB1

Molecular Weight

Mass (kDA):
24.61 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (2461642..2470789, complement)

Subcellular Localizations

Cytoplasm, cytosol. Nucleus. SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.