This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Sorting nexin-1 Antibodies
AND SNX1 ELISA kits, Sorting nexin-1 Proteins
Many biological assays use antibodies to detect Sorting nexin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sorting nexin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sorting nexin-1 antibodies...
Designing a Western blot for Sorting nexin-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SNX1 Western Blot GuideSNX1 Infographic by Boster Bio
All SNX1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A11003-3
100 μg/vial
Cat # A11003-3
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02692-2
100 μg/vial
Cat # A02692-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02692-1
100 μl/vial
Cat # M02692-1
100 μl/vial
SNX1 Overview
Facts about Sorting nexin-1.
Sorting nexin-1 (SNX1)
Involved in several stages of intracellular trafficking. Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex.
The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes into the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane to a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable).
Gene Information
| Human | |
|---|---|
| Gene Name: | SNX1 |
| Uniprot: | Q13596 |
| Entrez: | 6642 |
Family
| Belongs to: |
|---|
| sorting nexin family |
Alternative Names
HsT17379; MGC8664; SNX1Asorting nexin 1A; sorting nexin 1; sorting nexin-1; Vps5
Molecular Weight
Mass (kDA):
59.07 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q22.31 |
| Sequence: | 15; NC_000015.10 (64094066..64144231) |
Subcellular Localizations
Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Enriched on tubular elements of the early endosome membrane. Binds preferentially to highly curved membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:15498486). Colocalized with SORT1 to tubular endosomal membrane structures called endosome-to-TGN transp
Diseases
- Malignant Neoplasms
- Carcinoma
- Neoplasms
- Tissue Adhesions
- Cell Transformation, Neoplastic
- Essential Hypertension
- Colonic Neoplasms
- Malignant Tumor Of Colon
- Protein Deficiency
- Malignant Neoplasm Of Lung
- Parkinson Disease
- Carcinogenesis
Interacting Proteins
- AGTRAP
- ARL6IP1
- CMTM5
- FUNDC1
- RABAC1
- REEP6
- RTN3
- RTN4
- SNX2
- SNX32
Pathways
- Transport
- Localization
- Endocytosis
- Macropinocytosis
- Pathogenesis
- Rna Interference
- Cell Adhesion
- Protein Targeting
- Cell Cycle
- Receptor Recycling
- Endosomal Transport
- Cell Proliferation
- Vesicle Localization
PTMs
- Phosphorylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNX1
bosterbio.com/bosterbio-gene-info-cards/SNX1
References
PMID: 8638121 by Kurten R.C., et al. Enhanced degradation of EGF receptors by a sorting nexin, SNX1.
PMID: 9819414 by Haft C.R., et al. Identification of a family of sorting nexin molecules and characterization of their association with receptors.