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- Table of Contents
Designing a Western blot for Sorting nexin-9? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SNX9 Western Blot GuideFacts about Sorting nexin-9.
Plays a role in macropinocytosis. Promotes internalization of TNFR.
| Human | |
|---|---|
| Gene Name: | SNX9 |
| Uniprot: | Q9Y5X1 |
| Entrez: | 51429 |

| Belongs to: |
|---|
| sorting nexin family |

MST155; MSTP155; Protein SDP1; SDP1; SH3 and PX domain-containing protein 1; SH3PX1WISP; SH3PXD3ASH3 and PX domain-containing protein SH3PX1; sorting nexin 9; sorting nexin-9; WiskSH3 and PX domain-containing protein 3A
Mass (kDA):
66.592 kDA

| Human | |
|---|---|
| Location: | 6q25.3 |
| Sequence: | 6; NC_000006.12 (157716046..157945077) |
Widely expressed, with highest levels in heart and placenta, and lowest levels in thymus and peripheral blood leukocytes.
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin-coated vesicle. Golgi apparatus, trans-Golgi network. Cell projection, ruffle. Cytoplasm. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation. Colocalizes with the actin cytoskeleton at the cell membrane.





PMID: 11485546 by Teasdale R.D., et al. A large family of endosome-localized proteins related to sorting nexin 1.
PMID: 10531379 by Howard L., et al. Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.