SPCS1 Antibodies

AND SPCS1 ELISA kits, SPCS1 Proteins

Many biological assays use antibodies to detect SPCS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SPCS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SPCS1 antibodies...

We validate the specificity of these antibodies to SPCS1 by testing them on tissues known to express SPCS1 positively and negatively. Browse below to find the SPCS1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPCS1 Infographic by Boster Bio

All SPCS1 Products

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Product

Figures

Specificity

Applications

Price

Anti-SPCS1 Antibody (Center)

Human

$299
Cat # M12522
50 µl

SPCS1 (NM_014041) Human Over-expression Lysate

Human

$628
Cat # LS028972
20 µg, 100 µg

SPCS1 Overview

Facts about Signal peptidase complex subunit 1.

SPCS1 3D structure. Source: alphafold

Signal peptidase complex subunit 1 (SPCS1)

Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. .

Gene Information

Human
Gene Name:	SPCS1
Uniprot:	Q9Y6A9
Entrez:	28972

Family

Belongs to:

SPCS1 family

Alternative Names

EC 3.4; HSPC033; Microsomal signal peptidase 12 kDa subunit; signal peptidase 12kDa; signal peptidase complex subunit 1 homolog (S. cerevisiae); signal peptidase complex subunit 1; SPase 12 kDa subunit; SPC12SPC1; YJR010C-A

Molecular Weight

Mass (kDA):
18.298 kDA

Genomic Context


Human

Location:	3p21.1
Sequence:	3; NC_000003.12 (52706106..52711148)

Subcellular Localizations

Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPCS1

References

PMID: 8632014 by Kalies K.-U., et al. Membrane topology of the 12- and the 25-kDa subunits of the mammalian signal peptidase complex.

PMID: 24023390 by Catherman A.D., et al. Large-scale top down proteomics of the human proteome: membrane proteins, mitochondria, and senescence.