Cytospin-A Antibodies

AND SPECC1L ELISA kits, Cytospin-A Proteins

Many biological assays use antibodies to detect Cytospin-A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytospin-A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytospin-A antibodies...

We validate the specificity of these antibodies to Cytospin-A by testing them on tissues known to express SPECC1L positively and negatively. Browse below to find the SPECC1L antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPECC1L Infographic by Boster Bio

All SPECC1L Products

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Anti-Cytospin-A SPECC1L Antibody

Western blot analysis of extracts of various cell lines, using SPECC1L antibody at 1:1000 dilution

Human

IHC, WB

$405
Cat # A09120
100ul

Anti-SPECC1L Antibody Picoband®

Western blot analysis of SPECC1L using anti-SPECC1L antibody (A09120-1)

IF analysis of SPECC1L using anti-SPECC1L antibody (A09120-1)

Flow Cytometry analysis of HepG2 cells using anti-SPECC1L antibody (A09120-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A09120-1
100 µg/vial

SPECC1L Overview

Facts about Cytospin-A.

SPECC1L 3D structure. Source: alphafold

Cytospin-A (SPECC1L)

Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.

Gene Information

Human
Gene Name:	SPECC1L
Uniprot:	Q69YQ0
Entrez:	23384

Family

Belongs to:

cytospin-A family

Alternative Names

Cytokinesis And Spindle Organization A; Cytospin A; CYTSA; GBBB2; KIAA0376; OBLFC1; Renal Carcinoma Antigen NY-REN-22; SPECC1-Like Protein; SPECC1-Like; Sperm Antigen With Calponin Homology And Coiled-Coil Domains 1-Like

Molecular Weight

Mass (kDA):
124.602 kDA

Genomic Context


Human

Location:	22q11.23
Sequence:	22; NC_000022.11 (24270817..24417740)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell junction, gap junction. Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center.

Diseases

Oblique Facial Clefts
Cleft Palate
Cleft Face
Tissue Adhesions
Developmental Disabilities
Craniofacial Dysostosis

Eye Abnormalities

Pathways

Cell Adhesion

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPECC1L

References

PMID: 21703590 by Saadi I., et al. Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting.

PMID: 26111080 by Bhoj E.J., et al. Expanding the SPECC1L mutation phenotypic spectrum to include Teebi hypertelorism syndrome.