Testican-3 Antibodies

AND SPOCK3 ELISA kits, Testican-3 Proteins

Many biological assays use antibodies to detect Testican-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Testican-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Testican-3 antibodies...

We validate the specificity of these antibodies to Testican-3 by testing them on tissues known to express SPOCK3 positively and negatively. Browse below to find the SPOCK3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPOCK3 Infographic by Boster Bio

All SPOCK3 Products

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Product

Figures

Specificity

Applications

Price

Mouse Testican 3/SPOCK3 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ8BKV0
Starting from 4ug

SPOCK3 (NM_001040159) Human Over-expression Lysate

Human

$628
Cat # LS050859
20 µg, 100 µg

Anti-SPOCK3 Antibody Picoband®

Western blot analysis of SPOCK3 using anti-SPOCK3 antibody (A03151-1)

IF analysis of SPOCK3 using anti-SPOCK3 antibody (A03151-1)

Human

ELISA, IF, ICC, WB

$370
Cat # A03151-1
100 µg/vial

SPOCK3 Overview

Facts about Testican-3.

SPOCK3 3D structure. Source: alphafold

Testican-3 (SPOCK3)

May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP.

May interfere with tumor invasion. .

Gene Information

Human
Gene Name:	SPOCK3
Uniprot:	Q9BQ16
Entrez:	50859

Family

Belongs to:

No superfamily

Alternative Names

CWCV, and Kazal-like domains proteoglycan 3; HSAJ1454; sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3; SPOCK3; TES-3; Testican 3; TICN3

Molecular Weight

Mass (kDA):
49.429 kDA

Genomic Context


Human

Location:	4q32.3
Sequence:	4; NC_000004.12 (166733384..167234869, complement)

Tissue Specificity

Expressed in brain.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Neoplasms
Cell Invasion
Glioma
Leukemia, T-cell
Hereditary Pancreatic Carcinoma
Neoplasm Invasiveness
Exanthema
Malignant Neoplasms
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas
Adult T-cell Lymphoma/leukemia
Adenocarcinoma

Scrapie
Congenital Abnormality
Developmental Delay (disorder)
Glioblastoma
Severe Mental Retardation
Malignant Paraganglionic Neoplasm

Pathways

Tooth Eruption
Cell Migration
Invasive Growth

PTMs

Disulfide bond
Glycoprotein

Heparan sulfate
Proteoglycan

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPOCK3

References

PMID: 11751414 by Nakada M., et al. Suppression of membrane-type 1 matrix metalloproteinase (MMP)- mediated MMP-2 activation and tumor invasion by testican 3 and its splicing variant gene product, N-Tes.