SPRR2E Antibodies

AND SPRR2E ELISA kits, SPRR2E Proteins

Many biological assays use antibodies to detect SPRR2E, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SPRR2E in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SPRR2E antibodies...

We validate the specificity of these antibodies to SPRR2E by testing them on tissues known to express SPRR2E positively and negatively. Browse below to find the SPRR2E antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPRR2E Infographic by Boster Bio

All SPRR2E Products

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SPRR2E (NM_001024209) Human Recombinant Protein

Coomassie blue staining of purified SPRR2E protein

$1249
Cat # PROTP22531
20 µg

SPRR2E (NM_001024209) Human Over-expression Lysate

Human

$628
Cat # LS006704
20 µg, 100 µg

SPRR2E Overview

Facts about Small proline-rich protein 2E.

SPRR2E 3D structure. Source: alphafold

Small proline-rich protein 2E (SPRR2E)

Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase.

All that results in the formation of an insoluble envelope beneath the plasma membrane. .

Gene Information

Human
Gene Name:	SPRR2E
Uniprot:	P22531
Entrez:	6704

Family

Belongs to:

cornifin (SPRR) family

Alternative Names

Small proline-rich protein 2E

Molecular Weight

Mass (kDA):
7.855 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (153093135..153094526, complement)

Subcellular Localizations

Cytoplasm.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPRR2E

References

PMID: 3133554 by Kartasova T., et al. Isolation, characterization, and UV-stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes.

PMID: 11279051 by Cabral A., et al. Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function.