Squalene monooxygenase Antibodies

AND SQLE ELISA kits, Squalene monooxygenase Proteins

Many biological assays use antibodies to detect Squalene monooxygenase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Squalene monooxygenase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Squalene monooxygenase antibodies...

We validate the specificity of these antibodies to Squalene monooxygenase by testing them on tissues known to express SQLE positively and negatively. Browse below to find the SQLE antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Squalene monooxygenase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the SQLE Western Blot Guide

SQLE Infographic by Boster Bio

All SQLE Products

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Product

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Specificity

Applications

Price

Squalene Epoxidase (SQLE) (NM_003129) Human Over-expression Lysate

Human

$628
Cat # LS006713
20 µg, 100 µg

Anti-SQLE Antibody

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A06763-1
100 μl/vial

Anti-Squalene monooxygenase SQLE Antibody

Western blot analysis of HepG2, using SQLE antibody at 1:1940 dilution

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A06763
100ul

SQLE Overview

Facts about Squalene monooxygenase.

SQLE 3D structure. Source: alphafold

Squalene monooxygenase (SQLE)

Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be among the rate-limiting enzymes in this pathway. .

Gene Information

Human
Gene Name:	SQLE
Uniprot:	Q14534
Entrez:	6713

Family

Belongs to:

squalene monooxygenase family

Alternative Names

EC 1.14.99.7; ERG1; FLJ30795; squalene epoxidaseSE; squalene monooxygenase

Molecular Weight

Mass (kDA):
63.923 kDA

Genomic Context


Human

Location:	8q24.13
Sequence:	8; NC_000008.11 (124998505..125022283)

Subcellular Localizations

Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Atherosclerosis
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Hypercholesterolemia
Obesity
Cardiovascular Diseases
Dental Plaque
Mammary Neoplasms
Inflammation
Tumor Progression
Hypoxia

Malignant Neoplasm Of Lung
Carcinoma
Carcinoma, Pancreatic Ductal
Pancreatic Neoplasm
Malignant Neoplasm Of Ovary
Malignant Neoplasm Of Pancreas
Altitude Sickness

Pathways

Transport
Localization
Glycolysis
Secretion
Protein Catabolic Process
Response To Hypoxia
Regeneration
Tissue Regeneration
Cholesterol Efflux
Cell Cycle
Cholesterol Transport

Pathogenesis
Catabolic Process
Luteinization
Cholesterol Homeostasis
Cellular Response To Hypoxia

PTMs

Ubl conjugation

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SQLE

References

PMID: 9286711 by Nagai M., et al. Localization of the squalene epoxidase gene (SQLE) to human chromosome region 8q24.1.

PMID: 10666321 by Laden B.P., et al. Cloning, heterologous expression, and enzymological characterization of human squalene monooxygenase.