SRSF6 Antibodies

AND SRSF6 ELISA kits, SRSF6 Proteins

Many biological assays use antibodies to detect SRSF6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SRSF6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SRSF6 antibodies...

We validate the specificity of these antibodies to SRSF6 by testing them on tissues known to express SRSF6 positively and negatively. Browse below to find the SRSF6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for SRSF6? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the SRSF6 Western Blot Guide

SRSF6 Infographic by Boster Bio

All SRSF6 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SR protein repeat Rabbit Monoclonal Antibody

Western blot analysis of SR protein repeat expression in K562 cell lysate

Human

IHC, WB

$370
Cat # M04489
100 μl/vial

SRSF6 (NM_006275) Human Over-expression Lysate

Human

$628
Cat # LS006431
20 µg, 100 µg

SRSF6 Overview

Facts about Serine/arginine-rich splicing factor 6.

SRSF6 3D structure. Source: alphafold

Serine/arginine-rich splicing factor 6 (SRSF6)

Plays a role in constitutive splicing and modulates the choice of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10.

Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing.

Gene Information

Human
Gene Name:	SRSF6
Uniprot:	Q13247
Entrez:	6431

Family

Belongs to:

splicing factor SR family

Alternative Names

B52; FLJ08061; pre-mRNA splicing factor SRP55; Pre-mRNA-splicing factor SRP55; serine/arginine-rich splicing factor 6; SFRS6; Splicing factor, arginine/serine-rich 6MGC5045; splicing factor, arginine/serine-rich, 55 kDa; SR splicing factor 6; SRP55arginine/serine-rich splicing factor 6

Molecular Weight

Mass (kDA):
39.587 kDA

Genomic Context


Human

Location:	20q13.11
Sequence:	20; NC_000020.11 (43457893..43464243)

Subcellular Localizations

Nucleus. Nucleus speckle.

Diseases

Tumor Angiogenesis
Cell Transformation, Neoplastic
Melanoma
Malignant Neoplasms
Retinal Diseases
Pathologic Neovascularization
Diabetic Retinopathy
Disorder Of Eye
Autoimmunity
Sclerosis
Disease Of Capillaries
Dementia

Down Syndrome
Exudative Age-related Macular Degeneration
Premature Aging Syndrome
Diffuse Scleroderma
Immunologic Deficiency Syndromes
Fibrosis
Myeloid Leukemia

Interacting Proteins

LUC7L2

Pathways

Angiogenesis
Induction Of Apoptosis
Localization
Protein Phosphorylation
Cell Activation
Protein Splicing
T Cell Activation
Aging
Regulation Of Gene Expression
Nuclear Export
Rna Splicing

Mrna Splicing
Translation
Coagulation
Tissue Remodeling
Rna Processing

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SRSF6

References

PMID: 7556075 by Screaton G.R., et al. Identification and characterization of three members of the human SR family of pre-mRNA splicing factors.

PMID: 1577277 by Zahler A.M., et al. SR proteins: a conserved family of pre-mRNA splicing factors.