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- Table of Contents
Lupus La protein Antibodies
AND SSB ELISA kits, Lupus La protein Proteins
Many biological assays use antibodies to detect Lupus La protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lupus La protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lupus La protein antibodies...
Designing a Western blot for Lupus La protein? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SSB Western Blot GuideSSB Infographic by Boster Bio
All SSB Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00705-1
100 μg/vial
Cat # A00705-1
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05166-1
100 µg/vial
Cat # A05166-1
100 µg/vial
Human
ELISA
$540
Cat # EKC2327
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2327
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$480
Cat # EKC1540
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1540
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$480
Cat # EKC1765
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1765
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1776
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1776
1 kit, containing one 96-well plate and all necessary reagents
SSB Overview
Facts about Lupus La protein.
Lupus La protein (SSB)
Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | SSB |
| Uniprot: | P05455 |
| Entrez: | 6741 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
La autoantigen; La ribonucleoprotein; lupus La protein; member 3; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B (autoantigen La); SS-B; SS-B/La protein
Molecular Weight
Mass (kDA):
46.837 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q31.1 |
| Sequence: | 2; NC_000002.12 (169798871..169812064) |
Subcellular Localizations
Nucleus.
Diseases
- Lupus Erythematosus, Systemic
- Sjogren's Syndrome
- Autoimmune Reaction
- Autoimmune Diseases
- Primary Sj??gren's Syndrome
- Heart Block
- Neonatal Lupus Erythematosus
- Congenital Heart Block
- Malignant Neoplasms
- Neoplasms
- Connective Tissue Diseases
- Arthritis
- Lupus Erythematosus, Cutaneous
Pathways
- Single-stranded Dna Binding
- Dna Replication
- Dna Repair
- Pathogenesis
- Cell Killing
- Cell Death
- Localization
- Translation
- Cell Cycle
- Sos Response
- Immune Response
- Secretion
- Transport
PTMs
- Cleavage
- Phosphorylation
- Reduction
- Oxidation
- Biotinylation
- Citrullination
- Methylation
- Ubiquitination
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SSB
bosterbio.com/bosterbio-gene-info-cards/SSB
References
PMID: 2468131 by Chan E.K.L., et al. Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding.
PMID: 3192525 by Chambers J.C., et al. Genomic structure and amino acid sequence domains of the human La autoantigen.