Somatostatin receptor type 4 (SSTR4)

Receptor for somatostatin-14.

The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.

It's functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.