This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6.
Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney.
Human | |
---|---|
Gene Name: | ST6GALNAC6 |
Uniprot: | Q969X2 |
Entrez: | 30815 |
Belongs to: |
---|
glycosyltransferase 29 family |
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; CMP-NeuAC:(beta)-N-acetylgalactosaminide (alpha)2,6-sialyltransferase member VI; EC 2.4.99; EC 2.4.99.-; EC 2.4.99.7; GalNAc alpha-2,6-sialyltransferase VI; hST6GalNAc VI; RP11-203J24.3; Sialyltransferase 7F; sialytransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialytransferase) F; SIAT7F; SIAT7-F; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminidealpha-2,6-sialyltransferase 6; ST6GalNAc VI; ST6GALNAC6; ST6GALNACVI
Mass (kDA):
38.068 kDA
Human | |
---|---|
Location: | 9q34.11 |
Sequence: | 9; NC_000009.12 (127885321..127906764, complement) |
Expressed in kidney, in proximal tubule epithelial cells. Expressed in colon cell lines.
Golgi apparatus membrane; Single-pass type II membrane protein.
PMID: 12668675 by Tsuchida A., et al. Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides.
PMID: 15843597 by Harduin-Lepers A., et al. The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach.
*More publications can be found for each product on its corresponding product page