ST8SIA1 Antibodies

AND ST8SIA1 ELISA kits, ST8SIA1 Proteins

Many biological assays use antibodies to detect ST8SIA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ST8SIA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ST8SIA1 antibodies...

We validate the specificity of these antibodies to ST8SIA1 by testing them on tissues known to express ST8SIA1 positively and negatively. Browse below to find the ST8SIA1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ST8SIA1 Infographic by Boster Bio

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ST8SIA1 (NM_003034) Human Over-expression Lysate

Human

$628
Cat # LS006489
20 µg, 100 µg

ST8SIA1 Overview

Facts about Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase.

ST8SIA1 3D structure. Source: alphafold

Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (ST8SIA1)

Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid. .

Gene Information

Human
Gene Name:	ST8SIA1
Uniprot:	Q92185
Entrez:	6489

Family

Belongs to:

glycosyltransferase 29 family

Alternative Names

Alpha-2,8-sialyltransferase 8A; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; disialoganglioside (GD3) synthase; Ganglioside GD3 synthase; Ganglioside GT3 synthase; ganglioside-specific alpha-2,8-polysialyltransferase; GD3 synthase); GD3S; sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3synthase) A; sialyltransferase 8A (alpha-N-acetylneuraminate: alpha-2,8-sialyltransferase; Sialyltransferase 8A; Sialytransferase St8Sia I; SIAT8A; SIAT8-A; SIAT8EC 2.4.99.8; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; ST8SIA1; ST8SiaI

Molecular Weight

Mass (kDA):
40.519 kDA

Genomic Context


Human

Location:	12p12.1
Sequence:	12; NC_000012.12 (22193391..22334714, complement)

Tissue Specificity

Strongly expressed in melanoma cell lines, adult and fetal brain and to a lesser extent in adult and fetal lung.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Malignant Neoplasm Of Breast
Malignant Neoplasms
Neoplasms
Mammary Neoplasms
Sclerosis
Carcinoma
Multiple Sclerosis
Ductal Breast Carcinoma
Neoplasm Metastasis
Immunologic Deficiency Syndromes
Invasive Ductal Breast Carcinoma
Memory Disorders

Nervousness
Pain
Dental Plaque
Carcinoma, Lobular
Dysequilibrium Syndrome
Plaque, Amyloid

Pathways

Transport
Cell Death
Cell Differentiation
Cholesterol Transport
Rna Interference
Cholesterol Homeostasis

Cell-cell Adhesion

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ST8SIA1

References

PMID: 8195250 by Sasaki K., et al. Expression cloning of a GM3-specific alpha-2,8-sialyltransferase (GD3 synthase).

PMID: 8058740 by Nara K., et al. Expression cloning of a CMP-NeuAc:NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1'Cer alpha 2,8-sialyltransferase (GD3 synthase) from human melanoma cells.