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- Table of Contents
Synaptopodin Antibodies
AND SYNPO ELISA kits, Synaptopodin Proteins
Many biological assays use antibodies to detect Synaptopodin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptopodin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptopodin antibodies...
Designing a Western blot for Synaptopodin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SYNPO Western Blot GuideSYNPO Infographic by Boster Bio
All SYNPO Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03154-1
100 μg/vial
Cat # A03154-1
100 μg/vial
Human
$960
Cat # LS011346
20 µg, 100 µg
Cat # LS011346
20 µg, 100 µg
Human
$960
Cat # LS171024
20 µg, 100 µg
Cat # LS171024
20 µg, 100 µg
SYNPO Overview
Facts about Synaptopodin.
Synaptopodin (SYNPO)
Actin-associated protein which may play a role in regulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Appears to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SYNPO |
| Uniprot: | Q8N3V7 |
| Entrez: | 11346 |
Family
| Belongs to: |
|---|
| synaptopodin family |
Alternative Names
KIAA1029; Synaptopodin; SYNPO
Molecular Weight
Mass (kDA):
99.463 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q33.1 |
| Sequence: | 5; NC_000005.10 (150586026..150659214) |
Tissue Specificity
Expressed in cerebral cortex.
Subcellular Localizations
Cytoplasm, cytoskeleton. Cell junction, tight junction. Perikaryon. Cell projection, dendritic spine. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Cytoplasm, cytosol. Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses.
Diseases
- Kidney Diseases
- Proteinuria Of Undiagnosed Cause
- Glomerulosclerosis (disorder)
- Focal Glomerulosclerosis
- Neoplasms
- Segmental Glomerulosclerosis
- Diabetic Nephropathy
- Aids-associated Nephropathy
- Sclerosis
- Nephrotic Syndrome
- Renal Glomerular Disease
- Nephroblastoma
- Glomerulonephritis
Interacting Proteins
- ACTN1
Pathways
- Pathogenesis
- Localization
- Glomerular Filtration
- Dedifferentiation
- Excretion
- Gene Silencing
- Cell Migration
- Cell Cycle
- Cell Proliferation
- Transport
- Cell Division
- Membrane Depolarization
- Cell Motility
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SYNPO
bosterbio.com/bosterbio-gene-info-cards/SYNPO
References
PMID: 9314539 by Mundel P., et al. Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes.
PMID: 12042308 by Patrie K.M., et al. Interaction of two actin-binding proteins, synaptopodin and alpha- actinin-4, with the tight junction protein MAGI-1.