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- Table of Contents
Facts about Acyl-CoA desaturase 2.
Gives rise to a mix of 16:1 and 18:1 unsaturated fatty acids (PubMed:16443825). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides, particularly during embryonic development and in neonates (PubMed:16118274).
| Mouse | |
|---|---|
| Gene Name: | Scd2 |
| Uniprot: | P13011 |
| Entrez: | 20250 |

| Belongs to: |
|---|
| fatty acid desaturase type 1 family |

Acyl-CoA desaturase 2
Mass (kDA):
40.916 kDA

| Mouse | |
|---|---|
| Location: | 19 C3|19 37.98 cM |
| Sequence: | 19; |
Detected in brain and skin (PubMed:10545940, PubMed:11161812, PubMed:16118274). Highly expressed in brain, and detected at low levels in heart, stomach, lung and testis (PubMed:11161812, PubMed:12815040). Detected both in dermis and epidermis (PubMed:16118274).

PMID: 2570068 by Kaestner K.H., et al. Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase.
PMID: 10545940 by Zheng Y., et al. Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.