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- Table of Contents
Facts about Acyl-CoA desaturase 3.
Has a strong preference for saturated fatty acids with chain lengths of 14 or 16 carbon atoms (C14:0 and C16:0), and contains only very low activity with stearatate (C18:0) (PubMed:16443825, PubMed:26098370). Required for the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).
| Mouse | |
|---|---|
| Gene Name: | Scd3 |
| Uniprot: | Q99PL7 |
| Entrez: | 30049 |

| Belongs to: |
|---|
| fatty acid desaturase type 1 family |

Acyl-CoA desaturase 3
Mass (kDA):
41.432 kDA

| Mouse | |
|---|---|
| Location: | 19|19 C3 |
| Sequence: | 19; |
Detected in skin, but at lower levels compared to Scd1. Detected in the middlle part of the sebaceous gland, but not in hair follicle. Not detected in liver and brain.

PMID: 11161812 by Zheng Y., et al. Scd3--a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin.
PMID: 16118274 by Miyazaki M., et al. Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development.