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Alpha-1-antitrypsin 1-1 Antibodies

AND Serpina1a ELISA kits, Alpha-1-antitrypsin 1-1 Proteins

Many biological assays use antibodies to detect Alpha-1-antitrypsin 1-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alpha-1-antitrypsin 1-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alpha-1-antitrypsin 1-1 antibodies...

We validate the specificity of these antibodies to Alpha-1-antitrypsin 1-1 by testing them on tissues known to express Serpina1a positively and negatively. Browse below to find the Serpina1a antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Serpina1a Infographic by Boster Bio

Serpina1a protein infographic

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Anti-Alpha-1-Antitrypsin/Serpina1a Antibody (Monoclonal, 35S11)

boster box

Mouse, Rat

IHC, WB

$370
Cat # M33430
100 μl/vial

Serpina1a Overview

Facts about Alpha-1-antitrypsin 1-1.

Serpina1a 3D structure

Serpina1a 3D structure. Source: alphafold

Alpha-1-antitrypsin 1-1 (Serpina1a)

Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin.

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Gene Information

Mouse
Gene Name:	Serpina1a
Uniprot:	P07758
Entrez:	20700

Gene Information

Family

Belongs to:

serpin family

Family

Alternative Names

Aat2; Dom1; PI1; Serpin A1a; Spi1-1

Molecular Weight

Mass (kDA):
46.003 kDA

Molecular Weight

Genomic Context


Mouse

Location:	12 E\|12 52.98 cM
Sequence:	12;

Diseases

Alpha 1-antitrypsin Deficiency
Pulmonary Emphysema
Lung Diseases
Chronic Obstructive Airway Disease
Liver Diseases
Lung Diseases, Obstructive
Malignant Neoplasms
Carcinoma
Inflammation
Liver Cirrhosis
Neoplasms
Hereditary Diseases
Liver Carcinoma

Liver Neoplasms
Hemochromatosis
Fibrosis
Hepatitis
Neoplasm Metastasis
Malignant Paraganglionic Neoplasm
Lung Neoplasms

Disease

Pathways

Pathogenesis
Immune Response
Secretion
Localization
Cell Proliferation
Glycosylation
Cell Death
Cell Adhesion
Cell Migration
Secretory Pathway
Response To Stress
Regeneration
Proteolysis

Hypersensitivity
Inflammatory Response
Cell Cycle
Wound Healing
Fucosylation
Cytokine Production
Autophagy

Pathways

PTMs

Cleavage
Glycosylation
Phosphorylation

Oxidation
Methylation
Ubiquitination

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Serpina1a

References

PMID: 1946354 by Borriello F., et al. Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence.

PMID: 12408969 by Barbour K.W., et al. The murine alpha(1)-proteinase inhibitor gene family: polymorphism, chromosomal location, and structure.