Swap70 Antibodies

AND Swap70 ELISA kits, Swap70 Proteins

Many biological assays use antibodies to detect Swap70, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Swap70 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Swap70 antibodies...

We validate the specificity of these antibodies to Swap70 by testing them on tissues known to express Swap70 positively and negatively. Browse below to find the Swap70 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Swap70? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SWAP70 IHC Guide

Swap70 Infographic by Boster Bio

All Swap70 Products

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Product

Figures

Specificity

Applications

Price

Anti-SWAP70 Antibody Picoband®

Western blot analysis of SWAP70 using anti-SWAP70 antibody (A06972-3)

IHC analysis of SWAP70 using anti-SWAP70 antibody (A06972-3)

Human

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A06972-3
100 µg/vial

SWAP70 (NM_015055) Human Over-expression Lysate

Human

$628
Cat # LS023075
20 µg, 100 µg

SWAP70 (NM_015055) Human Recombinant Protein

Coomassie blue staining of purified SWAP70 protein

$1062
Cat # PROTQ9UH65
20 µg

Swap70 Overview

Facts about Switch-associated protein 70.

Switch-associated protein 70 (Swap70)

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. Additionally, it mediates signaling of membrane ruffling.

Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). .

Gene Information

Mouse
Gene Name:	Swap70
Uniprot:	Q6A028
Entrez:	20947

Family

Belongs to:

No superfamily

Alternative Names

KIAA0640SWAP-70FLJ39540; SWAP switching B-cell complex 70kDa subunit; SWAP70; switch-associated protein 70

Molecular Weight

Mass (kDA):
68.996 kDA

Genomic Context


Mouse

Location:	7 E3\|7 57.7 cM
Sequence:	7;

Tissue Specificity

Spleen. Expressed only in B-cells that have been induced to switch to various Ig isotypes.

Diseases

Tissue Adhesions
Neoplasms
Lymphoma
Autoimmunity
Neoplasm Invasiveness
Malignant Neoplasms
Inflammation
Cell Transformation, Neoplastic
B-cell Lymphomas
Behcet Syndrome
Immunologic Deficiency Syndromes
Tumor Angiogenesis
Hypergammaglobulinemia

Nervousness
Allergy
Cell Invasion
Sclerosis
Neoplasm Metastasis
Malnutrition
Malignant Neoplasm Of Breast

Pathways

Localization
Cell Activation
Immune Response
Cell Adhesion
Dna Recombination
Cell Differentiation
Cell Proliferation
Cell Growth
B Cell Activation
Mast Cell Activation
Chemotaxis
Cell Motility
Cell Development

Angiogenesis
Pathogenesis
Germinal Center Formation
Cell Migration
Tube Formation
Plasma Cell Differentiation
Nuclear Export

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Swap70

References

PMID: 9642267 by Borggrefe T., et al. A B-cell-specific DNA recombination complex.

PMID: 10382743 by Borggrefe T., et al. Cellular, intracellular, and developmental expression patterns of murine SWAP-70.