TAFA5 Antibodies

AND TAFA5 ELISA kits, TAFA5 Proteins

Many biological assays use antibodies to detect TAFA5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TAFA5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TAFA5 antibodies...

We validate the specificity of these antibodies to TAFA5 by testing them on tissues known to express TAFA5 positively and negatively. Browse below to find the TAFA5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TAFA5 Infographic by Boster Bio

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TAFA5 (NM_015381) Human Over-expression Lysate

Human

$628
Cat # LS025817
20 µg, 100 µg

TAFA5 Overview

Facts about Chemokine-like protein TAFA-5.

TAFA5 3D structure. Source: alphafold

Chemokine-like protein TAFA-5 (TAFA5)

Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein- coupled receptors (GPCRs), such as S1PR2 and FPR2 (By similarity). Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway (By similarity).

Blocks TNFSF11/RANKL- induced osteoclast formation from macrophages by inhibiting up- regulation of osteoclast fusogenic and differentiation genes (By similarity). Stimulation of macrophage migration and inhibition of osteoclast formation is mediated via GPCR FPR2 (By similarity).

Gene Information

Human
Gene Name:	TAFA5
Uniprot:	Q7Z5A7
Entrez:	25817

Family

Belongs to:

TAFA family

Alternative Names

Chemokine-like protein TAFA-5

Molecular Weight

Mass (kDA):
14.301 kDA

Genomic Context


Human

Location:	22q13.32
Sequence:	22; NC_000022.11 (48489553..48751932)

Tissue Specificity

Expressed in the subcutaneous and perirenal adipose tissue (at protein level) (PubMed:29453251). Highly expressed in adipose tissue with moderate expression in the brain and ovary (PubMed:29453251). Isoform 2: Brain-specific (PubMed:15028294).

Subcellular Localizations

Secreted.

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TAFA5

References

PMID: 15028294 by Tom Tang Y., et al. TAFA: a novel secreted family with conserved cysteine residues and restricted expression in the brain.

PMID: 29453251 by Wang Y., et al. Novel Adipokine, FAM19A5, Inhibits Neointima Formation After Injury Through Sphingosine-1-Phosphate Receptor 2.