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- Table of Contents
Facts about Taste receptor type 2 member 4.
In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. .
| Human | |
|---|---|
| Gene Name: | TAS2R4 |
| Uniprot: | Q9NYW5 |
| Entrez: | 50832 |

| Belongs to: |
|---|
| G-protein coupled receptor T2R family |

candidate taste receptor T2R4; taste receptor, type 2, member 4
Mass (kDA):
33.841 kDA

| Human | |
|---|---|
| Location: | 7q34 |
| Sequence: | 7; NC_000007.14 (141776674..141781691) |
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells. Expressed on airway ciliated epithelium.
Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. In airway epithelial cells, localizes to motile cilia.



PMID: 10761934 by Adler E., et al. A novel family of mammalian taste receptors.
PMID: 15496549 by Fischer A., et al. Evolution of bitter taste receptors in humans and apes.