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- Table of Contents
TBX3 Antibodies
AND TBX3 ELISA kits, TBX3 Proteins
Many biological assays use antibodies to detect TBX3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TBX3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TBX3 antibodies...
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TBX3 Infographic by Boster Bio
All TBX3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, WB
$370
Cat # M01107-1
100 μl/vial
Cat # M01107-1
100 μl/vial
TBX3 Overview
Facts about T-box transcription factor TBX3.
T-box transcription factor TBX3 (TBX3)
Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.
Acts as a negative regulator of PML function in cellular senescence. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TBX3 |
| Uniprot: | O15119 |
| Entrez: | 6926 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
bladder cancer related protein XHL; T-box 3; T-box protein 3; T-box transcription factor TBX3; TBX3; TBX3-ISO; ulnar mammary syndrome; UMS; XHL
Molecular Weight
Mass (kDA):
79.389 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q24.21 |
| Sequence: | 12; NC_000012.12 (114670255..114684175, complement) |
Tissue Specificity
Widely expressed.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Ulnar-mammary Syndrome Of Pallister
- Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Congenital Abnormality
- Hypoplasia
- Cell Transformation, Neoplastic
- Haploinsufficiency
- Melanoma
- Carcinoma
- Cardiac Arrhythmia
- Congenital Heart Defects
Interacting Proteins
- AES
- CA8
Pathways
- Senescence
- Limb Development
- Cell Proliferation
- Cardiac Conduction
- Mammary Gland Development
- Gland Development
- Cell Differentiation
- Heart Development
- Cell Cycle
- Cell Migration
- System Development
- Localization
- Methylation
PTMs
- Methylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TBX3
bosterbio.com/bosterbio-gene-info-cards/TBX3
References
PMID: 10468588 by He M.-L., et al. Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome.
PMID: 9207801 by Bamshad M., et al. Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome.