Thromboxane A2 receptor (TBXA2R)

Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that triggers a phosphatidylinositol-calcium second messenger system.

In the kidney, the binding of TXA2 into glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C.