Tgtp1 Antibodies

AND Tgtp1 ELISA kits, Tgtp1 Proteins

Many biological assays use antibodies to detect Tgtp1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tgtp1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tgtp1 antibodies...

We validate the specificity of these antibodies to Tgtp1 by testing them on tissues known to express Tgtp1 positively and negatively. Browse below to find the Tgtp1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Tgtp1 Infographic by Boster Bio

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Tgtp1 Overview

Facts about T-cell-specific guanine nucleotide triphosphate-binding protein 1.

Tgtp1 3D structure. Source: alphafold

T-cell-specific guanine nucleotide triphosphate-binding protein 1 (Tgtp1)

Involved in innate cell-autonomous resistance to intracellular pathogens, such as Toxoplasma gondii. Throughout avirulent form II T.

gondii infection, recruited into the parasitophorous vacuole (PV) membrane, resulting in PV vesiculation and rupture, and subsequent digestion of the parasite within the cytosol (PubMed:19265156, PubMed:24563254). Not recruited to virulent type I T.

Gene Information

Mouse
Gene Name:	Tgtp1
Uniprot:	Q62293
Entrez:	21822

Family

Belongs to:

TRAFAC class dynamin-like GTPase superfamily

Alternative Names

T-cell-specific guanine nucleotide triphosphate-binding protein 1

Molecular Weight

Mass (kDA):
47.121 kDA

Genomic Context


Mouse

Location:	11\|11 B1.2
Sequence:	11;

Tissue Specificity

Expressed in thymus and lymph nodes, predominantly T-cells. Not expressed by immature CD4(+) CD8(+) thymocytes (at protein level) (PubMed:7836757). Expressed in IFNG- stimulated macrophages (PubMed:7884320). Expressed at low levels in unstimulated astrocytes (PubMed:19285957). Due to sequence similarity with Tgtp2, it is impossible to assign unambiguously experimental data published in the literature to Tgtp1 or Tgtp2 gene.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tgtp1

References

PMID: 7884320 by Lafuse W.P., et al. Cloning and characterization of a novel cDNA that is IFN-gamma- induced in mouse peritoneal macrophages and encodes a putative GTP- binding protein.

PMID: 7836757 by Carlow D.A., et al. Isolation of a gene encoding a developmentally regulated T cell- specific protein with a guanine nucleotide triphosphate-binding motif.