Tolloid-like protein 1 Antibodies

AND TLL1 ELISA kits, Tolloid-like protein 1 Proteins

Many biological assays use antibodies to detect Tolloid-like protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tolloid-like protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tolloid-like protein 1 antibodies...

We validate the specificity of these antibodies to Tolloid-like protein 1 by testing them on tissues known to express TLL1 positively and negatively. Browse below to find the TLL1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TLL1 Infographic by Boster Bio

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TLL1 (NM_012464) Human Over-expression Lysate

Human

$960
Cat # LS007092
20 µg, 100 µg

TLL1 Overview

Facts about Tolloid-like protein 1.

TLL1 3D structure. Source: alphafold

Tolloid-like protein 1 (TLL1)

Protease which procedures procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development.

Predominant protease, which at the development, affects dorsal-ventral patterning and skeletogenesis. .

Gene Information

Human
Gene Name:	TLL1
Uniprot:	O43897
Entrez:	7092

Family

Belongs to:

No superfamily

Alternative Names

ASD6; EC 3.4.24; EC 3.4.24.19; TLL1; TLLEC 3.4.24.-; Tolloid Like 1; tolloid-like 1; tolloid-like protein 1

Molecular Weight

Mass (kDA):
114.709 kDA

Genomic Context


Human

Location:	4q32.3
Sequence:	4; NC_000004.12 (165873124..166105178)

Subcellular Localizations

Secreted.

Diseases

Congenital Heart Defects
Atrial Septal Defects
Fetal Stress
Stenosis
Neuroblastoma
Heart Septal Defects
Limb Deformities, Congenital
Aneurysm
Regurgitation
Neuromuscular Diseases
Hypoxia
Single Gene Defect
Dysplasia

Fibrosis
Malignant Neoplasms
Ventricular Septal Defects
Retinal Diseases
Congenital Absence
Charcot-marie-tooth Disease
4q Partial Monosomy Syndrome

Pathways

Gastrulation
Heart Development
Endoderm Formation
Cell Activation
Cell Development
T Cell Activation
Proteolysis
Neurogenesis
Ovulation
Methylation

Tissue Development
Flight
Heteroduplex Formation
Myoblast Differentiation
Secretion

PTMs

Cleavage
Demethylation

Phosphorylation
Methylation

Research Areas

Adaptive Immunity
Apoptosis
Diabetes Research
Immunology
Innate Immunity

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLL1

References

PMID: 10479448 by Scott I.C., et al. Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis.

PMID: 10896944 by Scott I.C., et al. Bone morphogenetic protein-1 processes probiglycan.