Tolloid-like protein 2 Antibodies

AND TLL2 ELISA kits, Tolloid-like protein 2 Proteins

Many biological assays use antibodies to detect Tolloid-like protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tolloid-like protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tolloid-like protein 2 antibodies...

We validate the specificity of these antibodies to Tolloid-like protein 2 by testing them on tissues known to express TLL2 positively and negatively. Browse below to find the TLL2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TLL2 Infographic by Boster Bio

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TLL2 (NM_012465) Human Over-expression Lysate

Human

$960
Cat # LS007093
20 µg, 100 µg

TLL2 Overview

Facts about Tolloid-like protein 2.

TLL2 3D structure. Source: alphafold

Tolloid-like protein 2 (TLL2)

Protease which especially processes pro-lysyl oxidase. Required for the embryonic development.

Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis. .

Gene Information

Human
Gene Name:	TLL2
Uniprot:	Q9Y6L7
Entrez:	7093

Family

Belongs to:

No superfamily

Alternative Names

EC 3.4.24; EC 3.4.24.19; KIAA0932EC 3.4.24.-; MGC133312; MGC133313; tolloid-like 2; tolloid-like protein 2

Molecular Weight

Mass (kDA):
113.557 kDA

Genomic Context


Human

Location:	10q24.1
Sequence:	10; NC_000010.11 (96364608..96513926, complement)

Subcellular Localizations

Secreted.

Diseases

Abnormal Degeneration
Myopathy
Fibrosis
Epidermolysis Bullosa
Muscular Atrophy
Tissue Adhesions

Epidermolysis Bullosa Dystrophica

Pathways

Proteolysis
Gastrulation
Myoblast Differentiation

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLL2

References

PMID: 10479448 by Scott I.C., et al. Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis.

PMID: 11313359 by Uzel M.I., et al. Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures.