TM7SF2 Antibodies

AND TM7SF2 ELISA kits, TM7SF2 Proteins

Many biological assays use antibodies to detect TM7SF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TM7SF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TM7SF2 antibodies...

We validate the specificity of these antibodies to TM7SF2 by testing them on tissues known to express TM7SF2 positively and negatively. Browse below to find the TM7SF2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TM7SF2 Infographic by Boster Bio

All TM7SF2 Products

Product

Figures

Specificity

Applications

Price

TM7SF2 (NM_003273) Human Over-expression Lysate

Human

$628
Cat # LS007108
100 µg

TM7SF2 Overview

Facts about Delta(14)-sterol reductase TM7SF2.

TM7SF2 3D structure. Source: alphafold

Delta(14)-sterol reductase TM7SF2 (TM7SF2)

Involved in the conversion of lanosterol to cholesterol. .

Gene Information

Human
Gene Name:	TM7SF2
Uniprot:	O76062
Entrez:	7108

Family

Belongs to:

ERG4/ERG24 family

Alternative Names

ANG1; C-14 sterol reductase; delta(14)-sterol reductase; delta-14-SR; DHCR14A; NET47; putative sterol reductase SR-1; sterol C14-reductase; transmembrane 7 superfamily member 2

Molecular Weight

Mass (kDA):
46.406 kDA

Genomic Context


Human

Location:	11q13.1
Sequence:	11; NC_000011.10 (65111854..65116408)

Tissue Specificity

Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.

Subcellular Localizations

Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Carcinoma
Dysplasia
Skeletal Dysplasia
Adenoma
Malignant Neoplasm Of Adrenal Cortex
Neoplasms
Pelger-huet Anomaly
Hydrops Fetalis
Mutation Abnormality
Neoplasm Metastasis
Bone Neoplasms
Tumors Of Adrenal Cortex
Carcinogenesis

Cartilage Development Disorder
Edema
Malignant Neoplasms
Hemorrhage
Follicular Adenoma
Bone Diseases
Bone Diseases, Developmental

Pathways

Methylation
Heterochromatin Organization
Cell Proliferation
Gene Silencing
Pathogenesis
Luteinization
Cortisol Secretion

Localization
Secretion

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TM7SF2

References

PMID: 9615229 by Lemmens I.H., et al. Identification and molecular characterization of TM7SF2 in the FAUNA gene cluster on human chromosome 11q13.

PMID: 9878250 by Holmer L., et al. The human lamin B receptor/sterol reductase multigene family.