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- Table of Contents
Facts about Transmembrane protein 115.
.
| Human | |
|---|---|
| Gene Name: | TMEM115 |
| Uniprot: | Q12893 |
| Entrez: | 11070 |

| Belongs to: |
|---|
| TMEM115 family |

PL6Placental protein 6; PP6; Protein PL6; transmembrane protein 115
Mass (kDA):
38.197 kDA

| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (50354750..50359521, complement) |
Expressed strongly in kidney and skeletal muscle, followed by liver, placenta, pancreas, and lung, with low amounts in heart and only traces in brain (PubMed:11085536). Widely expressed with ubiquitous expression in epithelial tissues (at protein level) (PubMed:17973242).
Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein.





PMID: 11085536 by Lerman M.I., et al. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes.
PMID: 17973242 by Ivanova A.V., et al. Loss of PL6 protein expression in renal clear cell carcinomas and other VHL-deficient tumours.