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- Table of Contents

Facts about Transmembrane protein 8B.
May Serve as a regulator of the EGFR pathway.
Probable tumor suppressor which may function in cell growth, proliferation and adhesion..
| Human | |
|---|---|
| Gene Name: | TMEM8B |
| Uniprot: | A6NDV4 |
| Entrez: | 51754 |

| Belongs to: |
|---|
| TMEM8 family |

C9orf127; chromosome 9 open reading frame 127; NAG-5; nasopharyngeal carcinoma expressed 6; nasopharyngeal carcinoma related protein; Nasopharyngeal carcinoma-associated gene 6 protein; NGX6MGC120460; Protein NAG-5; Protein NGX6; RP11-112J3.10; transmembrane protein 8B
Mass (kDA):
51.941 kDA

| Human | |
|---|---|
| Location: | 9p13.3 |
| Sequence: | 9; NC_000009.12 (35825817..35865515) |
[Isoform 2]: Cell membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Mitochondrion. Endoplasmic reticulum. Also detected in mitochondrion and endoplasmic reticulum (PubMed:17641538).





PMID: 11565907 by Li J., et al. Proteomic detection of changes in protein synthesis induced by NGX6 transfected in human nasopharyngeal carcinoma cells.
PMID: 15498789 by Ma J., et al. Role of a novel EGF-like domain-containing gene NGX6 in cell adhesion modulation in nasopharyngeal carcinoma cells.