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- Table of Contents
Facts about BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2.
Its interaction with RHOB may regulate apoptosis. May improve the PCNA-dependent DNA polymerase delta activity.
Human | |
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Gene Name: | TNFAIP1 |
Uniprot: | Q13829 |
Entrez: | 7126 |
Belongs to: |
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BACURD family |
B12; B61; BACURD2; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; BTB/POZ domain-containing protein TNFAIP1; EDP1; hBACURD2; MGC2317; Protein B12; tumor necrosis factor, alpha-induced protein 1 (endothelial); Tumor necrosis factor, alpha-induced protein 1, endothelial
Mass (kDA):
36.204 kDA
Human | |
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Location: | 17q11.2 |
Sequence: | 17; NC_000017.11 (28335671..28347009) |
Cytoplasm. Nucleus. Endosome. Colocalizes with RHOB in endosomes.
This Steven Boster Bio will provide information about the TNFAIP1Marker. We'll also discuss the TNFAIP1 Marker's history. This marker is essential because it identifies an individual gene in the human genome. It's highly sensitive and accurate, and can be used to diagnose many diseases including cancer.
The research into Alzheimer's disease (AD), may be enhanced by the use of TNFAIP1Marker. Recent research suggests that this protein may be involved in both physiological processes (AD disease) and biological processes. It is also regulated in the hippocampus by estrogen, and its promoter analysis identified a possible binding site for ERb. This is a fascinating finding, since Tnfaip1 may be involved in Alzheimer's-related diseases.
TNFAIP1 gene expression has been linked with the development of malignant tumors. It has been discovered that TNFAIP1 expression in certain types of cancers can increase the risk of invasion and metastasis. Although the biological function of this protein is still unknown, recent research suggests that it may play a role in cisplatin resistance. This is a hallmark of cancer. In addition, this protein is expressed in several types of cancer, including gastric, esophageal, head and neck, lung, and breast cancers.
In addition to its biological role, TNFAIPs are poorly understood, and the role they play in human diseases is still unclear. Basic research is necessary to understand how TNFAIPs operate in the body, and how these affect a variety of conditions. However, the importance of TNFAIP1 Marker applications cannot be overstated. Before pursuing clinical trials with TNFAIP1Marker applications, it is important to conduct extensive research on the gene and its function in your body.
Tnfaip1 has a high expression level and a significant role in many brain functions. Tnfaip1 played a significant role in reactivity against b-amyloid accumulation according to previous research. Tnfaip1 can be found in various tissues including the hippocampal cortex in this AD model.
Tnfaip1 antibody activity was found in the CA1 region of adult and e17.5 mice. Tnfaip1 immunoactivity was increased in ovariectomized and estrogen receptor antagonists. Bacurd2 is associated with the formation of neural circuits. It is one among the most important GTPases of the nervous system. It plays multiple roles in the brain, including neurogenesis.
Previous studies have shown that ERb-mediated estrogen stimulation is involved in regulation Tnfaip1 gene expression. Several other reports have described acute E2-mediated signaling actions in the brain. These signals are not dependent on classical nuclear-initiated Steroid Signaling. Several membrane ERs including ERX and G-protein-coupled receptacles were also identified.
If you are looking for Steven Boster's history, you are at the right place. The company has public records, including Steve's home address, previous addresses, and cell phone numbers. It even includes his known relatives. You can filter Steve's records by age or state to learn more about his history. Steve Boster's story is fascinating. You'll be able to find out where he grew up and who he went to school.
Steve Boster, born June 6, 1952, Joliet IL. He passed away June 6, 2022 at Madison, WI. He was the only child of Evelyn Meier (James Boster) He served in the U.S. Army and was a member of Concordia Hall in Staunton, Virginia. His two daughters, Crystal Boster & Natosha Peeck, as well 6 grandchildren and 4 brothers Jack & Sandra Boster are his survivors. His sister Lisa Milton, his nieces and nephews are also surviving.
PMID: 1370465 by Wolf F.W., et al. Characterization of a novel tumor necrosis factor-alpha-induced endothelial primary response gene.
PMID: 19637314 by Kim D.M., et al. RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells.