TNNC2 Antibodies

AND TNNC2 ELISA kits, TNNC2 Proteins

Many biological assays use antibodies to detect TNNC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNNC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNNC2 antibodies...

We validate the specificity of these antibodies to TNNC2 by testing them on tissues known to express TNNC2 positively and negatively. Browse below to find the TNNC2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNNC2 Infographic by Boster Bio

All TNNC2 Products

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Figures

Specificity

Applications

Price

Anti-Troponin C, skeletal muscle TNNC2 Antibody

Western blot analysis of extracts of various cell lines, using TNNC2 antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded human colon using TNNC2 antibody at dilution of 1:200

Immunohistochemistry of paraffin-embedded mouse lung using TNNC2 antibody at dilution of 1:200

Human, Mouse, Rat

IHC, WB

$405
Cat # A10108
100ul

Human Troponin C (1-160aa) Recombinant Protein

SDS-PAGE

$250
Cat # PROTP02585
Starting from 20ug

Troponin C (TNNC2) (NM_003279) Human Over-expression Lysate

Human

$628
Cat # LS007125
20 µg, 100 µg

TNNC2 Overview

Facts about Troponin C, skeletal muscle.

TNNC2 3D structure. Source: alphafold

Troponin C, skeletal muscle (TNNC2)

Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three elements: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which comprises the binding site for tropomyosin and Tn-C.

The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. .

Gene Information

Human
Gene Name:	TNNC2
Uniprot:	P02585
Entrez:	7125

Family

Belongs to:

troponin C family

Alternative Names

skeletal muscle; troponin C type 2 (fast); troponin C2, fast

Molecular Weight

Mass (kDA):
18.122 kDA

Genomic Context


Human

Location:	20q13.12
Sequence:	20; NC_000020.11 (45823214..45833329, complement)

Diseases

Arthrogryposis
Distal Arthrogryposis Syndrome
Muscle Contracture
Fracture Of First Cervical Vertebra
Congenital Abnormality
Congenital Musculoskeletal Anomalies
Diabetic Neuropathies
Diabetes Mellitus
Fetal Death
Hyperalgesia

Congenital Clubfoot
Diabetes Mellitus, Experimental
Hyperalgesias, Mechanical
Pain
Painful Diabetic Neuropathies

Interacting Proteins

TNNI3

Pathways

Muscle Contraction
Localization
Regulation Of Muscle Contraction
Flight
Cell Proliferation

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNNC2

References

PMID: 3166492 by Gahlmann R., et al. Differential expression of slow and fast skeletal muscle troponin C. Slow skeletal muscle troponin C is expressed in human fibroblasts.

PMID: 2373703 by Gahlmann R., et al. Cloning, structural analysis, and expression of the human fast twitch skeletal muscle troponin C gene.