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- Table of Contents
TNNI1 Antibodies
AND TNNI1 ELISA kits, TNNI1 Proteins
Many biological assays use antibodies to detect TNNI1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNNI1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNNI1 antibodies...
Designing a Western blot for TNNI1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TNNI1 Western Blot GuideTNNI1 Infographic by Boster Bio
All TNNI1 Products
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TNNI1 Overview
Facts about Troponin I, slow skeletal muscle.
Troponin I, slow skeletal muscle (TNNI1)
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TNNI1 |
| Uniprot: | P19237 |
| Entrez: | 7135 |
Family
| Belongs to: |
|---|
| troponin I family |
Alternative Names
DKFZp451O223; slow-twitch isoform; SSTNI; TNN1; troponin I type 1 (skeletal, slow); troponin I, skeletal, slow; troponin I, slow skeletal muscle
Molecular Weight
Mass (kDA):
21.692 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q32.1 |
| Sequence: | 1; NC_000001.11 (201403784..201421730, complement) |
Tissue Specificity
Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes.
Diseases
- Hypertrophy
- Hypertrophic Cardiomyopathy
- Cardiomyopathies
- Acute Coronary Syndrome
- Cardiomyopathy, Hypertrophic, Familial
Interacting Proteins
- MDFI
- PNMA1
- TNNC1
Pathways
- Striated Muscle Contraction
- Muscle Contraction
- Response To Stress
- Membrane Depolarization
- Cell Development
- Regulation Of Striated Muscle Contraction
- Cell Communication
PTMs
- Acetylation
Research Areas
- Cell Biology
- Cellular Markers
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNNI1
bosterbio.com/bosterbio-gene-info-cards/TNNI1
References
PMID: 2365354 by Wade R., et al. cDNA sequence, tissue-specific expression, and chromosomal mapping of the human slow-twitch skeletal muscle isoform of troponin I.
PMID: 8144655 by Corin S.J., et al. Structure and expression of the human slow twitch skeletal muscle troponin I gene.