TNNI3K Antibodies

AND TNNI3K ELISA kits, TNNI3K Proteins

Many biological assays use antibodies to detect TNNI3K, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNNI3K in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNNI3K antibodies...

We validate the specificity of these antibodies to TNNI3K by testing them on tissues known to express TNNI3K positively and negatively. Browse below to find the TNNI3K antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNNI3K Infographic by Boster Bio

All TNNI3K Products

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TNNI3K (NM_015978) Human Over-expression Lysate

Human

$960
Cat # LS051086
20 µg, 100 µg

Anti-TNNI3K Antibody Picoband®

Western blot analysis of TNNI3K using anti-TNNI3K antibody (A06499-2)

Flow Cytometry analysis of HEL cells using anti-TNNI3K antibody (A06499-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A06499-2
100 μg/vial

TNNI3K Overview

Facts about Serine/threonine-protein kinase TNNI3K.

TNNI3K 3D structure. Source: alphafold

Serine/threonine-protein kinase TNNI3K (TNNI3K)

May play a role in cardiac physiology. .

Gene Information

Human
Gene Name:	TNNI3K
Uniprot:	Q59H18
Entrez:	51086

Family

Belongs to:

protein kinase superfamily

Alternative Names

CARKCardiac ankyrin repeat kinase; EC 2.7.11.1; MGC142099; MGC33828; serine/threonine-protein kinase TNNI3K; TNNI3 interacting kinase; TNNI3-interacting kinase

Molecular Weight

Mass (kDA):
92.851 kDA

Genomic Context


Human

Location:	1p31.1
Sequence:	1; NC_000001.11 (74235387..74544428)

Tissue Specificity

Highly expressed in both adult and fetal heart.

Subcellular Localizations

Nucleus. Cytoplasm. Expressed at lower levels in the cytoplasm.

Diseases

Cardiomyopathies
Heart Diseases
Hypertrophy
Obesity
Infarction
Cardiomyopathy, Hypertrophic, Familial
Sudden Cardiac Death
Hypertrophic Cardiomyopathy
Heart Failure
Diabetes Mellitus
Restrictive Cardiomyopathy
Cardiac Death

Myocardial Ischemia
Coronary Heart Disease
Coxsackievirus Infections
Cardiac Arrhythmia
Cardiac Hypertrophy
Pediatric Obesity
De Novo Mutation

Interacting Proteins

TNNI3

Pathways

Response To Stress
Reverse Transcription
Sarcomere Organization
Tropism
Pathogenesis
Localization
Cardiac Conduction

Syncytium Formation

PTMs

Phosphorylation

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNNI3K

References

PMID: 12721663 by Zhao Y., et al. Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I.

PMID: 24925317 by Theis J.L., et al. TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy.