TNP2 Antibodies

AND TNP2 ELISA kits, TNP2 Proteins

Many biological assays use antibodies to detect TNP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNP2 antibodies...

We validate the specificity of these antibodies to TNP2 by testing them on tissues known to express TNP2 positively and negatively. Browse below to find the TNP2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNP2 Infographic by Boster Bio

All TNP2 Products

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Anti-Nuclear transition protein 2 TNP2 Antibody

Western blot (WB) analysis of TNP2 polyclonal antibody at 1:500 dilution
Lane1:Hela whole cell lysate
Lane2:PC12 whole cell lysate

Human, Rat

$405
Cat # A09707
100ul

TNP2 (NM_005425) Human Over-expression Lysate

Human

$628
Cat # LS007142
20 µg, 100 µg

TNP2 Overview

Facts about Nuclear transition protein 2.

TNP2 3D structure. Source: alphafold

Nuclear transition protein 2 (TNP2)

Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.

Gene Information

Human
Gene Name:	TNP2
Uniprot:	Q05952
Entrez:	7142

Family

Belongs to:

nuclear transition protein 2 family

Alternative Names

Nuclear transition protein 2

Molecular Weight

Mass (kDA):
15.641 kDA

Genomic Context


Human

Location:	16p13.13
Sequence:	16; NC_000016.10 (11267857..11269325, complement)

Tissue Specificity

Expressed by spermatids (at protein level).

Subcellular Localizations

Nucleus. Chromosome. Loaded onto the nucleosomes of condensing spermatids (By similarity). Nuclear import is ATP-dependent and nucleolar localization requires the protein to be phosphorylated (By similarity).

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNP2

References

PMID: 8428967 by Nelson J.E., et al. Linkage of human spermatid-specific basic nuclear protein genes. Definition and evolution of the P1-->P2-->TP2 locus.

PMID: 7983046 by Nelson J.E., et al. Characterization of a human locus in transition.