TPST1 Antibodies

AND TPST1 ELISA kits, TPST1 Proteins

Many biological assays use antibodies to detect TPST1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TPST1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TPST1 antibodies...

We validate the specificity of these antibodies to TPST1 by testing them on tissues known to express TPST1 positively and negatively. Browse below to find the TPST1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TPST1 Infographic by Boster Bio

All TPST1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human TPST1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTO60507
Starting from 4ug

TPST1 (NM_003596) Human Over-expression Lysate

Human

$628
Cat # LS008460
20 µg, 100 µg

Anti-TPST1 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A11120
100 μl/vial

TPST1 Overview

Facts about Protein-tyrosine sulfotransferase 1.

TPST1 3D structure. Source: alphafold

Protein-tyrosine sulfotransferase 1 (TPST1)

Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate. .

Gene Information

Human
Gene Name:	TPST1
Uniprot:	O60507
Entrez:	8460

Family

Belongs to:

protein sulfotransferase family

Alternative Names

EC 2.8.2.20; protein-tyrosine sulfotransferase 1; TPST1; Tyrosylprotein Sulfotransferase 1; tyrosylprotein sulfotransferase 1TPST-1; tyrosylprotein sulfotransferase-1

Molecular Weight

Mass (kDA):
42.188 kDA

Genomic Context


Human

Location:	7q11.21
Sequence:	7; NC_000007.14 (66205314..66360443)

Tissue Specificity

Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Tissue Adhesions
Infertility
Atherosclerosis
Exocrine Pancreatic Insufficiency
Congenital Musculoskeletal Anomalies
Degenerative Polyarthritis
Cardiovascular Diseases
Asthma
Hyperlipidemia
Primary Hypothyroidism
Hematological Disease

Pulmonary Hypertension
Rheumatoid Arthritis
Asphyxia
Hypothyroidism
Male Infertility
Failure To Thrive

Pathways

Sulfation
Cell Adhesion
Reverse Transcription
Coagulation
Exocytosis
Pathogenesis
Spermatogenesis

Secretion

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TPST1

References

PMID: 9501187 by Ouyang Y.-B., et al. Tyrosylprotein sulfotransferase: purification and molecular cloning of an enzyme that catalyzes tyrosine O-sulfation, a common posttranslational modification of eukaryotic proteins.

PMID: 9733778 by Ouyang Y.-B., et al. Molecular cloning and expression of human and mouse tyrosylprotein sulfotransferase-2 and a tyrosylprotein sulfotransferase homologue in Caenorhabditis elegans.