TRAT1 Antibodies

AND TRAT1 ELISA kits, TRAT1 Proteins

Many biological assays use antibodies to detect TRAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRAT1 antibodies...

We validate the specificity of these antibodies to TRAT1 by testing them on tissues known to express TRAT1 positively and negatively. Browse below to find the TRAT1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRAT1 Infographic by Boster Bio

All TRAT1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TRAT1 Antibody Picoband®

Western blot analysis of TRAT1 using anti-TRAT1 antibody (A11223)

Flow Cytometry analysis of U251 cells using anti-TRAT1 antibody (A11223)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A11223
100 μg/vial

TRIM (TRAT1) (NM_016388) Human Over-expression Lysate

Human

$628
Cat # LS050852
20 µg, 100 µg

TRIM (TRAT1) (NM_016388) Human Recombinant Protein

Coomassie blue staining of purified TRAT1 protein

$1249
Cat # PROTQ6PIZ9
20 µg

Anti-TRIM Purified TRAT1 Monoclonal Antibody

Western blotting analysis of human Jurkat T cell line lysate (1% laurylmaltoside); non-reduced sample, immunostained by mAb TRIM-04 and goat anti-mouse IgG (H+L)-HRP conjugate

Human

Flow Cytometry, IP, WB

$315
Cat # M11223
0.1 mg

TRAT1 Overview

Facts about T-cell receptor-associated transmembrane adapter 1.

TRAT1 3D structure. Source: alphafold

T-cell receptor-associated transmembrane adapter 1 (TRAT1)

Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. .

Gene Information

Human
Gene Name:	TRAT1
Uniprot:	Q6PIZ9
Entrez:	50852

Family

Belongs to:

No superfamily

Alternative Names

pp29/30; T cell receptor associated transmembrane adaptor 1; T cell receptor interacting molecule; T-cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TCRIM; TRAT1; TRIM; TRIMHSPC062

Molecular Weight

Mass (kDA):
21.211 kDA

Genomic Context


Human

Location:	3q13.13
Sequence:	3; NC_000003.12 (108822786..108855005)

Tissue Specificity

Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).

Subcellular Localizations

Cell membrane; Single-pass type III membrane protein.

Diseases

Neoplasm Metastasis
Metastatic Melanoma
Neoplasms
Melanoma
Decreased Immunologic Activity [pe]

Pathways

Immune Response
Transport
Cell Proliferation

PTMs

Disulfide bond

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRAT1

References

PMID: 9687533 by Bruyns E., et al. T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide- linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane.

PMID: 11390434 by Kirchgessner H., et al. The transmembrane adaptor protein TRIM regulates T-cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain.