TRAV20 Antibodies

AND TRAV20 ELISA kits, TRAV20 Proteins

Many biological assays use antibodies to detect TRAV20, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRAV20 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRAV20 antibodies...

We validate the specificity of these antibodies to TRAV20 by testing them on tissues known to express TRAV20 positively and negatively. Browse below to find the TRAV20 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRAV20 Infographic by Boster Bio

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TRAV20 Overview

Facts about T cell receptor alpha variable 20.

TRAV20 3D structure. Source: alphafold

T cell receptor alpha variable 20 (TRAV20)

V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.

Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.

Gene Information

Human
Gene Name:	TRAV20
Uniprot:	A0A0B4J274
Entrez:	28663

Family

Belongs to:

No superfamily

Alternative Names

T cell receptor alpha variable 20

Molecular Weight

Mass (kDA):
12.682 kDA

Genomic Context


Human

Location:	14q11.2
Sequence:	14; NC_000014.9 (22040663..22041153)

Subcellular Localizations

Cell membrane.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRAV20

References

PMID: 27568928 by Petersen J., et al. Diverse T cell receptor gene usage in HLA-DQ8-associated celiac disease converges into a consensus binding solution.