TRAV38-2DV8 Antibodies

AND TRAV38-2DV8 ELISA kits, TRAV38-2DV8 Proteins

Many biological assays use antibodies to detect TRAV38-2DV8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRAV38-2DV8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRAV38-2DV8 antibodies...

We validate the specificity of these antibodies to TRAV38-2DV8 by testing them on tissues known to express TRAV38-2DV8 positively and negatively. Browse below to find the TRAV38-2DV8 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRAV38-2DV8 Infographic by Boster Bio

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TRAV38-2DV8 Overview

Facts about T cell receptor alpha variable 38-2/delta variable 8.

TRAV38-2DV8 3D structure. Source: alphafold

T cell receptor alpha variable 38-2/delta variable 8 (TRAV38-2DV8)

V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.

Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.

Gene Information

Human
Gene Name:	TRAV38-2DV8
Uniprot:	A0JD32
Entrez:	28643

Family

Belongs to:

No superfamily

Alternative Names

T cell receptor alpha variable 38-2/delta variable 8

Molecular Weight

Mass (kDA):
13.278 kDA

Genomic Context


Human

Location:	14q11.2
Sequence:	14; NC_000014.9 (22281151..22281748)

Subcellular Localizations

Cell membrane.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRAV38-2DV8

References

PMID: 9110172 by Boysen C., et al. Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones.