TRBD1 Antibodies

AND TRBD1 ELISA kits, TRBD1 Proteins

Many biological assays use antibodies to detect TRBD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRBD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRBD1 antibodies...

We validate the specificity of these antibodies to TRBD1 by testing them on tissues known to express TRBD1 positively and negatively. Browse below to find the TRBD1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRBD1 Infographic by Boster Bio

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TRBD1 Overview

Facts about T cell receptor beta diversity 1.

T cell receptor beta diversity 1 (TRBD1)

D area of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors that are important to the immune response and are present on the cell surface of T lymphocytes.

Recognize peptide-major histocompatibility (MH) (pMH) complexes that are exhibited by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR into pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.

Gene Information

Human
Gene Name:	TRBD1
Uniprot:	P0DPI4
Entrez:	28637

Family

Belongs to:

No superfamily

Alternative Names

T cell receptor beta diversity 1

Molecular Weight

Mass (kDA):
0.29 kDA

Genomic Context


Human

Location:	7q34
Sequence:	7; NC_000007.14 (142786213..142786224)

Subcellular Localizations

Cell membrane.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRBD1

References

PMID: 12853948 by Hillier L.W., et al. The DNA sequence of human chromosome 7.

PMID: 15040585 by Nikolich-Zugich J., et al. The many important facets of T-cell repertoire diversity.