TRBV6-2 Antibodies

AND TRBV6-2 ELISA kits, TRBV6-2 Proteins

Many biological assays use antibodies to detect TRBV6-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRBV6-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRBV6-2 antibodies...

We validate the specificity of these antibodies to TRBV6-2 by testing them on tissues known to express TRBV6-2 positively and negatively. Browse below to find the TRBV6-2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRBV6-2 Infographic by Boster Bio

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TRBV6-2 Overview

Facts about T cell receptor beta variable 6-2.

TRBV6-2 3D structure. Source: alphafold

T cell receptor beta variable 6-2 (TRBV6-2)

V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.

Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333). Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.