TRHDE Antibodies

AND TRHDE ELISA kits, TRHDE Proteins

Many biological assays use antibodies to detect TRHDE, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRHDE in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRHDE antibodies...

We validate the specificity of these antibodies to TRHDE by testing them on tissues known to express TRHDE positively and negatively. Browse below to find the TRHDE antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRHDE Infographic by Boster Bio

All TRHDE Products

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TRHDE (NM_013381) Human Over-expression Lysate

Human

$960
Cat # LS029953
20 µg, 100 µg

TRHDE Overview

Facts about Thyrotropin-releasing hormone-degrading ectoenzyme.

TRHDE 3D structure. Source: alphafold

Thyrotropin-releasing hormone-degrading ectoenzyme (TRHDE)

Specific inactivation of TRH following its launch. .

Gene Information

Human
Gene Name:	TRHDE
Uniprot:	Q9UKU6
Entrez:	29953

Family

Belongs to:

peptidase M1 family

Alternative Names

EC 3.4.19.6; FLJ22381; PAP-II; PAP-IIthyroliberinase; PGPEP2; Pyroglutamyl-peptidase II; Thyroliberinase; thyrotropin-releasing hormone degrading enzyme; thyrotropin-releasing hormone-degrading ectoenzyme; TRHDE; TRH-DE; TRHdegrading Ectoenzyme; TRH-degrading Ectoenzyme; TRH-DEthyrotropin-releasing hormone degrading ectoenzyme; TRH-specific aminopeptidase

Molecular Weight

Mass (kDA):
117 kDA

Genomic Context


Human

Location:	12q21.1
Sequence:	12; NC_000012.12 (72087288..72666662)

Tissue Specificity

Predominantly expressed in brain.

Subcellular Localizations

Membrane; Single-pass type II membrane protein.

Diseases

Arthritis
Graves Disease
Rheumatoid Arthritis
Hyperthyroidism

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRHDE

References

PMID: 10491199 by Schomburg L., et al. Human TRH-degrading ectoenzyme cDNA cloning, functional expression, genomic structure and chromosomal assignment.