TRIM35 Antibodies

AND TRIM35 ELISA kits, TRIM35 Proteins

Many biological assays use antibodies to detect TRIM35, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRIM35 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRIM35 antibodies...

We validate the specificity of these antibodies to TRIM35 by testing them on tissues known to express TRIM35 positively and negatively. Browse below to find the TRIM35 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRIM35 Infographic by Boster Bio

All TRIM35 Products

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Product

Figures

Specificity

Applications

Price

Anti-TRI35 TRIM35 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A11229
100ul

TRIM35 (NM_171982) Human Over-expression Lysate

Human

$628
Cat # LS023087
20 µg, 100 µg

TRIM35 Overview

Facts about Tripartite motif-containing protein 35.

TRIM35 3D structure. Source: alphafold

Tripartite motif-containing protein 35 (TRIM35)

Reduce FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell development (PubMed:25263439). Involved in the cell death mechanism (By similarity).

Gene Information

Human
Gene Name:	TRIM35
Uniprot:	Q9UPQ4
Entrez:	23087

Family

Belongs to:

TRIM/RBCC family

Alternative Names

HLS5Hemopoietic lineage switch protein 5; KIAA1098MGC17233; MAIR; tripartite motif containing 35; tripartite motif-containing 35; tripartite motif-containing protein 35

Molecular Weight

Mass (kDA):
56.54 kDA

Genomic Context


Human

Location:	8p21.2
Sequence:	8; NC_000008.11 (27284886..27311272, complement)

Subcellular Localizations

Cytoplasm. Nucleus. Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies (By similarity).

Diseases

Acute Erythroblastic Leukemia
Neoplasms
Leukoencephalopathy, Progressive Multifocal
Malignant Neoplasms
Liver Carcinoma
Leukemia
Liver Neoplasms

Carcinoma
Carcinogenesis

Pathways

Cell Cycle
Cell Growth
Pathogenesis

PTMs

Acetylation

Phosphoprotein

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRIM35

References

PMID: 14662771 by Lalonde J.-P., et al. HLS5, a novel RBCC (ring finger, B box, coiled-coil) family member isolated from a hemopoietic lineage switch, is a candidate tumor suppressor.

PMID: 25263439 by Chen Z., et al. TRIM35 Interacts with pyruvate kinase isoform M2 to suppress the Warburg effect and tumorigenicity in hepatocellular carcinoma.