TRMT112 Antibodies

AND TRMT112 ELISA kits, TRMT112 Proteins

Many biological assays use antibodies to detect TRMT112, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRMT112 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRMT112 antibodies...

We validate the specificity of these antibodies to TRMT112 by testing them on tissues known to express TRMT112 positively and negatively. Browse below to find the TRMT112 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRMT112 Infographic by Boster Bio

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HSPC152 (TRMT112) (NM_016404) Human Over-expression Lysate

Human

$628
Cat # LS051504
20 µg, 100 µg

TRMT112 Overview

Facts about Multifunctional methyltransferase subunit TRM112-like protein.

TRMT112 3D structure. Source: alphafold

Multifunctional methyltransferase subunit TRM112-like protein (TRMT112)

Acts as an activator of both rRNA/tRNA and protein methyltransferases (PubMed:25851604). Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA (PubMed:25851604).

The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L- methionine as methyl donor (PubMed:18539146). The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (PubMed:20308323).

Gene Information

Human
Gene Name:	TRMT112
Uniprot:	Q9UI30
Entrez:	51504

Family

Belongs to:

TRM112 family

Alternative Names

HSPC152; HSPC170; TRM112; TRM112-like protein; TRMT11-2; tRNA methyltransferase 11-2 homolog (S. cerevisiae); tRNA methyltransferase 112 homolog

Molecular Weight

Mass (kDA):
14.199 kDA

Genomic Context


Human

Location:	11q13.1
Sequence:	11; NC_000011.10 (64316460..64318596, complement)

Subcellular Localizations

Nucleus, nucleoplasm. Cytoplasm, perinuclear region. Localizes to a polarized perinuclear structure, overlapping partially with the Golgi and lysosomes (PubMed:25851604).