TTLL12 Antibodies

AND TTLL12 ELISA kits, TTLL12 Proteins

Many biological assays use antibodies to detect TTLL12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TTLL12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TTLL12 antibodies...

We validate the specificity of these antibodies to TTLL12 by testing them on tissues known to express TTLL12 positively and negatively. Browse below to find the TTLL12 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for TTLL12? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the TTLL12 IHC Guide

TTLL12 Infographic by Boster Bio

All TTLL12 Products

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Applications

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Anti-TTLL12 Antibody Picoband®

Western blot analysis of TTLL12 using anti-TTLL12 antibody (A14589-1)

IHC analysis of TTLL12 using anti-TTLL12 antibody (A14589-1)

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A14589-1
100 μg/vial

TTLL12 (NM_015140) Human Over-expression Lysate

Human

$628
Cat # LS023170
20 µg, 100 µg

TTLL12 Overview

Facts about Tubulin--tyrosine ligase-like protein 12.

TTLL12 3D structure. Source: alphafold

Tubulin--tyrosine ligase-like protein 12 (TTLL12)

Gene Information

Human
Gene Name:	TTLL12
Uniprot:	Q14166
Entrez:	23170

Family

Belongs to:

tubulin--tyrosine ligase family

Alternative Names

dJ526I14.2; KIAA0153FLJ41795; tubulin tyrosine ligase-like family, member 12; tubulin--tyrosine ligase-like protein 12

Molecular Weight

Mass (kDA):
74.404 kDA

Genomic Context


Human

Location:	22q13.2
Sequence:	22; NC_000022.11 (43166622..43187134, complement)

Subcellular Localizations

Cytoplasm. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus. Predominantly localizes in the cytoplasm (PubMed:28011935). Partially colocalizes with vimentin in prostate cancer cells (PubMed:20162578).

Diseases

Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Neoplasm Metastasis
Neoplasms

Metastatic Prostate Cancer

Interacting Proteins

DNAJB1
EEF1A1
EEF1A2

Pathways

Methylation
Protein Methylation
Immune Response
Dna Methylation
Demethylation

PTMs

Hydroxylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TTLL12

References

PMID: 20162578 by Wasylyk C., et al. Tubulin tyrosine ligase like 12 links to prostate cancer through tubulin posttranslational modification and chromosome ploidy.

PMID: 23251473 by Brants J., et al. Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis.