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- Table of Contents

Facts about Twinfilin-2.
By capping the barbed ends of filaments, in addition, it regulates motility. Seems to play an significant role in clathrin-mediated endocytosis and supply of endocytic organelles.
| Human | |
|---|---|
| Gene Name: | TWF2 |
| Uniprot: | Q6IBS0 |
| Entrez: | 11344 |

| Belongs to: |
|---|
| actin-binding proteins ADF family |

A6-related protein; A6RPFLJ56277; hA6RP; protein tyrosine kinase 9-like (A6-related protein); Protein tyrosine kinase 9-like; PTK9L protein tyrosine kinase 9-like (A6-related protein); PTK9LA6r; twinfilin, actin-binding protein, homolog 2 (Drosophila); Twinfilin-1-like protein; twinfilin-2
Mass (kDA):
39.548 kDA

| Human | |
|---|---|
| Location: | 3p21.2 |
| Sequence: | 3; NC_000003.12 (52228612..52239158, complement) |
Ubiquitously expressed (at protein level).
Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, stereocilium. Perinuclear and G-actin-rich cortical actin structure sublocalization.





PMID: 10406962 by Rohwer A., et al. Cloning, expression and characterization of an A6 related protein.