TXNL4A Antibodies

AND TXNL4A ELISA kits, TXNL4A Proteins

Many biological assays use antibodies to detect TXNL4A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TXNL4A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TXNL4A antibodies...

We validate the specificity of these antibodies to TXNL4A by testing them on tissues known to express TXNL4A positively and negatively. Browse below to find the TXNL4A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TXNL4A Infographic by Boster Bio

All TXNL4A Products

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Product

Figures

Specificity

Applications

Price

Anti-Thioredoxin-like protein 4A TXNL4A Antibody

Western blot analysis of extracts of various cell lines, using TXNL4A antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A08434
100ul

TXNL4A (NM_006701) Human Recombinant Protein

Coomassie blue staining of purified TXNL4A protein

$1249
Cat # PROTP83876
20 µg

TXNL4A (NM_006701) Human Over-expression Lysate

Human

$628
Cat # LS010907
20 µg, 100 µg

TXNL4A Overview

Facts about Thioredoxin-like protein 4A.

TXNL4A 3D structure. Source: alphafold

Thioredoxin-like protein 4A (TXNL4A)

Plays role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). .

Gene Information

Human
Gene Name:	TXNL4A
Uniprot:	P83876
Entrez:	10907

Family

Belongs to:

DIM1 family

Alternative Names

DIB1; DIM1 protein homolog; DIM1Thioredoxin-like U5 snRNP protein U5-15kD; HsT161; Spliceosomal U5 snRNP-specific 15 kDa protein; thioredoxin-like 4; thioredoxin-like 4A; thioredoxin-like protein 4A; TXNL4; U5-15kD

Molecular Weight

Mass (kDA):
16.786 kDA

Genomic Context


Human

Location:	18q23
Sequence:	18; NC_000018.10 (79970813..80033936, complement)

Subcellular Localizations

Nucleus.

Diseases

Microcephaly
Mutation, Out-of-frame
Atresia
Developmental Delay (disorder)
Cleft Palate
Dysostoses
Sequelae Aspects
Haploinsufficiency
Mandibulofacial Dysostosis

Choanal Atresia
Sensorineural Hearing Loss (disorder)
Senile Plaques
Neurofibrillary Tangles

Interacting Proteins

CD2BP2
EXOC5
LZTS2

Pathways

Pathogenesis

PTMs

Disulfide bond

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TXNL4A

References

PMID: 10610776 by Reuter K., et al. Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15kD protein.

PMID: 11054566 by Zhang Y.-Z., et al. Evidence that Dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for Dim1 interactions with hnRNP F and Npw38/PQBP-1.