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- Table of Contents

Facts about Tripartite motif-containing protein 30A.
Negatively regulates Toll-like receptor (TLR)-mediated activation of NFKB by promoting degradation of TAB2 and TAB3 and preventing TRAF6 autoubiquitination. Negatively regulates production of reactive oxygen species (ROS) which inhibits activation of the NLRP3 inflammasome complex.
| Mouse | |
|---|---|
| Gene Name: | Trim30a |
| Uniprot: | P15533 |
| Entrez: | 20128 |

| Belongs to: |
|---|
| No superfamily |

Tripartite motif-containing protein 30A
Mass (kDA):
57.33 kDA

| Mouse | |
|---|---|
| Location: | 7 E3|7 55.69 cM |
| Sequence: | 7; |
Highly expressed in spleen and lymph nodes (at protein level).

PMID: 2965815 by Patarca R., et al. rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1.
PMID: 11331580 by Reymond A., et al. The tripartite motif family identifies cell compartments.