UBE2S Antibodies

AND UBE2S ELISA kits, UBE2S Proteins

Many biological assays use antibodies to detect UBE2S, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UBE2S in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UBE2S antibodies...

We validate the specificity of these antibodies to UBE2S by testing them on tissues known to express UBE2S positively and negatively. Browse below to find the UBE2S antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for UBE2S? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the UBE2S Western Blot Guide

UBE2S Infographic by Boster Bio

All UBE2S Products

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Product

Figures

Specificity

Applications

Price

Anti-UBE2S Antibody Picoband®

Western blot analysis of UBE2S using anti-UBE2S antibody (A03045-2)

IF analysis of UBE2S using anti-UBE2S antibody (A03045-2)

Flow Cytometry analysis of HL-60 cells using anti-UBE2S antibody (A03045-2)

Human, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03045-2
100 μg/vial

UBE2S (NM_014501) Human Over-expression Lysate

Human

$628
Cat # LS027338
20 µg, 100 µg

UBE2S (NM_014501) Human Recombinant Protein

$1249
Cat # PROTQ16763
20 µg

UBE2S Overview

Facts about Ubiquitin-conjugating enzyme E2 S.

UBE2S 3D structure. Source: alphafold

Ubiquitin-conjugating enzyme E2 S (UBE2S)

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:22496338). Catalyzes 'Lys-11'-linked polyubiquitination.

Acts as an important factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle- regulated ubiquitin ligase that controls progression through mitosis. Acts by especially elongating'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit (PubMed:19820702, PubMed:19822757, PubMed:27259151).

Gene Information

Human
Gene Name:	UBE2S
Uniprot:	Q16763
Entrez:	27338

Family

Belongs to:

ubiquitin-conjugating enzyme family

Alternative Names

E2-24K; E2-EPF; E2-EPF5; E2-EPF52; E2-EPFEC 6.3.2.19; E2EPFEPF5; EPF5; UBE2S; Ubiquitin carrier protein S; ubiquitin-conjugating enzyme E2 S; ubiquitin-conjugating enzyme E2-24 kD; Ubiquitin-conjugating enzyme E2-24 kDa; Ubiquitin-conjugating enzyme E2-EPF5; ubiquitin-conjugating enzyme E2S; Ubiquitin-protein ligase S

Molecular Weight

Mass (kDA):
23.845 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (55399745..55408439, complement)

Interacting Proteins

ANAPC2

Pathways

Cell Cycle
Mitosis
Cell Division
Proteolysis
Rna Interference
Protein Ubiquitination

Spindle Assembly

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UBE2S

References

PMID: 1379239 by Liu Z., et al. cDNA cloning of a novel human ubiquitin carrier protein. An antigenic domain specifically recognized by endemic pemphigus foliaceus autoantibodies is encoded in a secondary reading frame of this human epidermal transcript.

PMID: 16819549 by Jung C.R., et al. E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis.