UBTF Antibodies

AND UBTF ELISA kits, UBTF Proteins

Many biological assays use antibodies to detect UBTF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UBTF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UBTF antibodies...

We validate the specificity of these antibodies to UBTF by testing them on tissues known to express UBTF positively and negatively. Browse below to find the UBTF antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UBTF Infographic by Boster Bio

All UBTF Products

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Specificity

Applications

Price

UBF1 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HeLa/Jurkat cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1586
1 kit, containing one 96-well plate and all necessary reagents

Anti-Phospho-UBF (S484) UBTF Antibody

Western blot analysis of lysates from HeLa cells treated with calyculinA 50ng/ml 30', using UBF (Phospho-Ser484) Antibody

Western blot analysis of lysates from HeLa cells treated with calyculinA 50ng/ml 30

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using UBF (Phospho-Ser484) Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A05134S484
100ul

UBF1 (UBTF) (NM_001076683) Human Over-expression Lysate

UBF1 (UBTF) Human Over-expression Lysates NM_001076683

Human

$628
Cat # LS007343
20 µg, 100 µg

Anti-UBF1 Rabbit Monoclonal Antibody

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature

Human, Mouse, Rat

IHC, WB

$370
Cat # M05134
100 µl/vial

Anti-Phospho-UBF1 (S484) Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M05134S484
100 µl/vial

UBTF Overview

Facts about Nucleolar transcription factor 1.

UBTF 3D structure. Source: alphafold

Nucleolar transcription factor 1 (UBTF)

Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.

Gene Information

Human
Gene Name:	UBTF
Uniprot:	P17480
Entrez:	7343

Family

Belongs to:

No superfamily

Alternative Names

90-KDa Nucleolus Organizer Region Autoantigen; Autoantigen NOR-90; NOR-90; nucleolar transcription factor 1; UBF; UBF1; UBF-1; UBF2; UBFUBF-1; upstream binding transcription factor, RNA polymerase I; Upstream-binding factor 1

Molecular Weight

Mass (kDA):
89.406 kDA

Genomic Context


Human

Location:	17q21.31
Sequence:	17; NC_000017.11 (44205036..44221304, complement)

Subcellular Localizations

Nucleus, nucleolus.

Diseases

Head And Neck Neoplasms
Steroid Sulfatase Deficiency Disease

Interacting Proteins

MYC
RUNX2
SET

Pathways

Localization
Transposition
Cell Proliferation
Rrna Transcription
Chromatin Remodeling

PTMs

Deacetylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UBTF

References

PMID: 2330041 by Jantzen H.M., et al. Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins.

PMID: 1940801 by Chan E.K.L., et al. Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor.