UCP3 Antibodies

AND UCP3 ELISA kits, UCP3 Proteins

Many biological assays use antibodies to detect UCP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UCP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UCP3 antibodies...

We validate the specificity of these antibodies to UCP3 by testing them on tissues known to express UCP3 positively and negatively. Browse below to find the UCP3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for UCP3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the UCP3 Western Blot Guide

UCP3 Infographic by Boster Bio

All UCP3 Products

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Product

Figures

Specificity

Applications

Price

Anti-UCP3 Antibody Picoband®

Western blot analysis of UCP3 using anti-UCP3 antibody (A01769-3)

Human, Mouse, Rat

$370
Cat # A01769-3
100 μg/vial

UCP3 (NM_003356) Human Over-expression Lysate

UCP3 Human Over-expression Lysates NM_003356

Human

$628
Cat # LS007352
20 µg, 100 µg

UCP3 Overview

Facts about Mitochondrial uncoupling protein 3.

UCP3 3D structure. Source: alphafold

Mitochondrial uncoupling protein 3 (UCP3)

UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the kind of heat.

May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.

Gene Information

Human
Gene Name:	UCP3
Uniprot:	P55916
Entrez:	7352

Family

Belongs to:

mitochondrial carrier (TC 2.A.29) family

Alternative Names

mitochondrial uncoupling protein 3; SLC25A9Solute carrier family 25 member 9; UCP 3; uncoupling protein 3 (mitochondrial, proton carrier); Uncoupling protein-3

Molecular Weight

Mass (kDA):
34.216 kDA

Genomic Context


Human

Location:	11q13.4
Sequence:	11; NC_000011.10 (74000277..74009237, complement)

Tissue Specificity

Only in skeletal muscle and heart. Is more expressed in glycolytic than in oxidative skeletal muscles.

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

Diseases

Obesity
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Insulin Resistance
Insulin Sensitivity
Nervousness
Malignant Neoplasms
Neoplasms
Inflammation
Dysequilibrium Syndrome
Cardiovascular Diseases
Metabolic Diseases

Diabetes Mellitus, Experimental
Hyperinsulinism
Cachexia
Hyperglycemia
Hypothyroidism
Hyperthyroidism

Pathways

Transport
Oxidative Phosphorylation
Fatty Acid Oxidation
Secretion
Energy Homeostasis
Aging
Insulin Secretion
Localization
Lipid Oxidation
Electron Transport
Pathogenesis
Proton Transport
Electron Transport Chain

Response To Cold
Glycolysis
Fatty Acid Transport
Swimming
Tricarboxylic Acid Cycle
Uniport
Adp Phosphorylation

PTMs

Oxidation
Phosphorylation
Cleavage
Glutathionylation
Acetylation
Sumoylation
Carboxylation

Dephosphorylation
Deglutathionylation
Ribosylation
Nitration
Reduction
Deacetylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UCP3

References

PMID: 9180264 by Boss O., et al. Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression.

PMID: 9325252 by Solanes G., et al. The human uncoupling protein-3 gene. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts.